Recent studies have shown that anti-VEGF treatment not only is effective for treating DBE, but is also effective for slowing progression of diabetic retinopathy, including PDP, so anti-VEGF is increasingly used as a first-line treatment for PDP. Focal/grid laser is sometimes applied before anti-VEGF injections, sometimes on the same day or a few days after an anti-VEGF injection, and sometimes only when DBE fails to improve adequately after six months of anti-VEGF therapy. Eventually, diabetic retinopathy, glaucoma or both can lead to complete vision loss. What are the symptoms of diabetic retinopathy and DBE? New blood vessels grow on the retina. Incidence; Causes and Development Diabetic retinopathy is the leading cause of blindness in people ages 20 to 74.  In the more advanced stage of diabetic retinopathy, called proliferative retinopathy, fragile new blood vessels grow around the retina and in the vitreous humour a clear substance that fills the eye. Severe loss of vision or even blindness can result if surgery is not performed to reattach the retina. This test measures pressure inside the eye. Many people with diabetes have mild NPDR, which usually does not affect their vision.

The dip in the retina is the fovea, a region of the macula where vision is normally at its sharpest. People with diabetes do have a higher risk of blindness than people without diabetes. As the disease progresses, symptoms include: The earliest sign of diabetic retinopathy that your doctor may detect is the formation of micro aneurysms.